Sources are top-left, audio flows right thru filters and such. Maths and Turing Machine, plus P/S are lower-left to group mod sources, then the audio processing chain starts with the Freez to the Magneto. I/O is on lower right at the end of the processing set.
From my experience, following this sort of upward-on-left (control) and downward-on-right (audio) ordering method seems to work very well. You can clearly see the audio signal flow across the top row until it has to drop down to the processing and output, and the modulation is down and left so that it can reach "into" this path to affect the behavior of your sources and modifiers.
However, if you don't have a Clouds on hand already, you'll need to rethink that module, as it's been discontinued for quite some time. OTOH, removing it for a smaller third-party version would add some open space, and if that's the case, I strongly recommend adding some envelope gens to this alongside the Maths.