The +12V rail is the main one that modules use. Not everything requires the -12V rail, and these days the trend with the +5V rail is for some manufacturers to put the downconversion onboard the module that needs it. But the current headroom issue is per rail, since the two 12V and 5V rails are all powered by different circuits. And you can pop the +12V by overdrawing, but leave the -12 and +5 (unless the +5 requires the +12) more or less intact. So if you've got 1500 mA on the +12V rail, and the P/S feeding the rail is rated for 2A, you're fine. But getting too much further above that 1500 mA gets a bit dicey, particularly if the build is very module-dense as each module will have SOME inrush...and adding each of those up can get you into the trouble zone pretty quickly.