Even when working in polyphonic or multitimbral patches, this layout method works...because it has the built-in asset of, if something sounds wrong, you can be very sure just by listening as to where the wrongness is. So it actually tends to make complex patches easier to sort out and use. Yes, the patchcord jungle is fairly daunting...but if you're talking about complex orders of control, several layers of patching, etc, it's going to get that way anyway, so adopting a method that's worked for decades (I based it on the ARP 2600 layout, basically) you get the complexity AND a method for controlling it that makes a bit more sense.